What is Armodafinil?

Armodafinil is a medicine taken orally. It promotes wakefulness. The medicine is also similar to modafinil (Provigil). Armodafinil is capable of promoting wakefulness as it stimulates the brain. However, scientists are not sure about the mechanism of action of armodafinil. buy armodafinilProbably, it increases the dopamine amount in the brain and reduces the reuptake of dopamine into nerves. Dopamine is a chemical neurotransmitter, which is necessary because using it nerves can communicate with each other. Armodafinil was approved by FDA in June 2007. You should store Armodafinil at room temperature, 20-30 C (or 68-77 F).

Armodafinil is used for improving wakefulness. It is necessary in case of obstructive sleep apnea/hypoapnea syndrome, narcolepsy, and shift work sleep problems. Doctors recommend150 or 250 mg every morning. They also recommend 150 mg daily one hour prior to the work.

Armodafinil is capable of increasing or decreasing the enzyme activity in the liver which metabolize or eliminate other drugs. So, use of this medicine can increase levels of other drugs and decrease levels of some other drugs. So, it may result in lower effectiveness or toxicity of other medicines.

if you take the following drugs with Armodafinil, then they will show reduced effectiveness- cyclosporine (Sandimmune), ethinyl estradiol (Estrace, Climara, Estraderm, Menostar) (present in many birth control pills), midazolam (Versed), and triazolam (Halcion).

Omeprazole (Prilosec), warfarin (Coumadin), diazepam (Valium), propranolol (Inderal), imipramine (Tofranil), desipramine (Norpramin), clomipramine (Anafranil), phenytoin (Dilantin) and mephenytoin (Mesantoin) are some of the drugs which show toxicity when taken with armodafinil.

Elements like Carbamazepine (Tegretol), phenobarbital, and rifampin (Rifadin) can increase elimination of armodafinil by the liver and thereby reduced the effectiveness. . Ketoconazole (Nizoral), itraconazole (Sporanox) and erythromycin reduces the elimination of armodafinil by the liver and thereby increases its effectiveness.

Not many studies have been done in case of pregnant women. If armodafinil is used during pregnancy, it may result in decreased fetal development and spontaneous abortion.

There are certain side effects associated with use of armodafinil. These side effects include anxiety, dizziness, diarrhea, dry mouth, insomnia, nausea, fatigue, and rash. You may also encounter some of the rare side effects like angioedema, difficulty swallowing, bronchospasms, and reversible psychosis.

If you experience any of the side effects or allergic reaction to Nuvigil such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat, you should immediately contact your doctor and seek medical help. In case of the following side effects, you should immediately seek medical help-

•  fever, sore throat, headache, and vomiting with a severe blistering, peeling, and red skin rash;

•  the first sign of any type of skin rash, no matter how mild;

•  bruising, severe tingling, numbness, pain, muscle weakness;

•  easy bruising or bleeding;

•  mouth sores, trouble swallowing;

•  upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

•  depression, confusion, hallucinations, aggression, unusual thoughts or behavior;

•  chest pain, uneven heart beats.

Nuvigil also results in some less serious side effects-

•  headache, dizziness;

•  feeling nervous or anxious;

•  nausea, diarrhea, upset stomach;

•  trouble sleeping (insomnia); or

•  dry mouth.

 

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